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August 27, 2019


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NEMBUTAL Sodium Solution (pentobarbital sodium injection, USP) is available in the following sizes:
20-mL multiple-dose vial, 1 g per vial (NDC 67386-501-52); and 50-mL multiple-dose vial, 2.5 g per vial (NDC 67386-501-55).
Each mL contains:
Pentobarbital Sodium, derivative of barbituric acid.......................................50 mg
Propylene glycol........................................................................................40% v/v
Alcohol ............................................................................................................10%
Water for Injection..............................................................................................qs (pH adjusted to approximately 9.5 with hydrochloric acid and/or sodium hydroxide.)
Vial stoppers are latex free.


Nembutal sodium pentobarbital powder, unlike other lethal drugs, may not require any additional drugs. Only anti-emetic drugs must be taken in advance, in order to prevent any vomiting from occurring. This has been partially endorsed by experts in administration of the death penalty, whereby a pure barbiturate method has been deemed less painful and more successful than prior 3-drug approaches and newer concoctions involving e.g. Midazolam (in the traditional 3-drug approach, a barbiturate was one of the components). There have, however, been reports of less successful attempts, the cause of which have been debated. The use of pentobarbital-only has also been called into question by some experts on capital punishment. sodium phenobarbital effects , phenobarbital sodium solubility in ethanol, phenobarbital sodium drugbank, phenobarbital sodium pediatric, phenobarbital sodium structure,

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